CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM375
Family Name Beta-3 adrenergic receptor and Beta-2 adrenergic receptor ligand N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-3-(2-pyrrol-1-ylethyl)benzamide family
No. of Seeds 2 No. of Other Members 22
Family Centroid CFAMM00310917 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Beta-2 adrenergic receptor Binder Superfamily 3
Class Class 1619

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Histone deacetylase 1 Inhibitor MS-275 Family 4 41
Coagulation factor X Inhibitor Otamixaban Family 9 21
Tyrosine-protein phosphatase non-receptor type 1 Ligand 6-(oxa... 1 5
Transient receptor potential cation channel subfamily V member... 6 23
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
Beta-3 adrenergic receptor ligand N-[4-[2-[[(2R)-2-hydroxy-2-p... 1 10
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 4 7
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 4 4
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 5 1
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 4 2
Beta-3 adrenergic receptor ligand SureCN5704018 family 4 1
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 2 1
Beta-3 adrenergic receptor ligand N-[4-[2-[[(2R)-2-hydroxy-2-p... 4 10
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 2 3
MAP kinase-activated protein kinase 2 inhibitor SureCN14188371... 1 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00310917 CHEMBL1078496 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-3-(2-pyrrol-1-ylethyl)benzamide
CFAMM00310907 CHEMBL127451 Bioactive 3-[[(E)-1-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]anilino]-2-nitroethenyl]amino]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26816 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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