CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM37825
Family Name Tyrosyl-DNA phosphodiesterase 1 and Inositol monophosphatase 1 inhibitor TPEN family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00510242 Functional Category Bioactive
Superfamily Inositol monophosphatase 1 and Tyrosyl-DNA phosphodiesterase 1 Binder Superfamily 2
Class Class 2594

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor Ethion... 5 68
G protein-activated inward rectifier potassium channel 4 Ligan... 3 48
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 19
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... 2 2
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Cytochrome P450 11B1, mitochondrial Inhibitor 2-methyl-1,2-di-... 8 15
Metabotropic glutamate receptor 5 Ligand 5-(2-methylquinolin-7... 4 3
Metabotropic glutamate receptor 5 Ligand 7-m-tolyl-1,6-naphthy... 4 2
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 0
Neuronal acetylcholine receptor subunit alpha-6 ligand AGN-PC-... 2 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 10 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 2
Ras-related protein Rab-9A and Niemann-Pick C1 protein inhibit... 1 2
Potassium voltage-gated channel subfamily A member 5 and Inter... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00510242 CHEMBL1472575 Bioactive TPEN

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27698 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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