CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3784
Family Name Vasopressin V2 receptor ligand [2-chloro-4-(prop-2-enylamino)phenyl]-(2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone family
No. of Seeds 3 No. of Other Members 14
Family Centroid CFAMM00350629 Functional Category Bioactive
Superfamily Vasopressin V2 receptor and Prelamin-A/C Binder Superfamily
Class Class 1375

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Pan-DAC Inhibitor AR-42 Family 21 153
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
C-C chemokine receptor type 5 Ligand Tak-220 Family 8 56
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 19 186
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Cruzipain Inhibitor 5-chloro-1-(4-chloro-benzyl)-1h-indole-2,3... 3 13
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Vasopressin V2 receptor and Vasopressin V1a receptor ligand N-... 5 8
Vasopressin V1a receptor and Vasopressin V2 receptor ligand CH... 3 5
Vasopressin V1a receptor ligand AGN-PC-074VJP family 3 1
Rho-associated protein kinase 2 inhibitor N-(7-chloro-1-oxo-2H... 13 42
Vasopressin V1a receptor ligand AGN-PC-074VSA family 3 0
Acetylcholinesterase inhibitor CHEMBL1651130 family 2 3
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 2 4
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 4 3
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Cellular tumor antigen p53 and Inositol monophosphatase 1 inhi... 1 12
Prelamin-A/C and Lysine-specific demethylase 4E inhibitor 4-(4... 2 3
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 4 19
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A ... 2 2
P2X purinoceptor 7 inhibitor AGN-PC-050YNC family 1 6
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(3... 2 4
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[5-... 3 0
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 5 1
Sodium-dependent noradrenaline transporter inhibitor AGN-PC-07... 1 1
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 8
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 3
Cannabinoid receptor 1 ligand SureCN14463736 family 2 0
Vasopressin V2 receptor and Vasopressin V1a receptor ligand (2... 4 0
C-X-C chemokine receptor type 3 ligand AGN-PC-00PW0E family 3 11
C-C chemokine receptor type 2 ligand AGN-PC-00D2HV family 2 2
Vasopressin V1a receptor and Vasopressin V2 receptor ligand Su... 3 0
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00350636 CHEMBL343945 Bioactive [2-chloro-4-(ethylamino)phenyl]-(7-chloro-2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
CFAMM00350629 CHEMBL136644 Bioactive [2-chloro-4-(prop-2-enylamino)phenyl]-(2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
CFAMM00350632 CHEMBL340893 Bioactive (2-chloro-4-pyrrolidin-1-ylphenyl)-(2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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