CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM379
Family Name Peroxisome proliferator-activated receptor alpha and Peroxisome proliferator-activated receptor gamma ligand 4-methyl-N-[[4-(2,2,2-trifluoroethylsulfonylamino)phenyl]methyl]-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide family
No. of Seeds 4 No. of Other Members 8
Family Centroid CFAMM00266500 Functional Category Bioactive with Natural Product
Superfamily Beta-lactamase and Thyroid hormone receptor beta Binder Superfamily
Class Class 2131

Cousin Family NamesSeedsMembers
Cyclin-dependent kinase 5 Inhibitor 3-(2-phenylthiazol-4-yl)qu... 2 44
Transient receptor potential cation channel subfamily V member... 1 17
Phosphoribosylaminoimidazolecarboxamide formyltransferase Inhi... 1 13
Cysteine protease and Cruzipain inhibitor N-[(E,3S)-1-(benzene... 1 1
Coagulation factor X and Trypsin-1 inhibitor 4-(3-carbamimidoy... 2 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor th... 1 3
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor (3... 1 5
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 4 4
Transient receptor potential cation channel subfamily V member... 22 3
Cathepsin K inhibitor N-(cyanomethyl)-5,5-difluoro-2-[2-methyl... 1 0
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-04XJR1 family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00310962 CHEMBL1490019 Bioactive 4-methyl-2-phenyl-N-(4-sulfamoylphenyl)-1,3-thiazole-5-carboxamide
CFAMM00310953 CHEMBL1078675 Bioactive N-[(E,3S)-1-(benzenesulfonyl)-5-phenylpent-1-en-3-yl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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