Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.
CFAM Family ID CFFBM38 Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor AC1MQSAW family No. of Seeds 14
No. of Other Members 0
Family Centroid CFAMM00306224 Functional Category Bioactive
Superfamily Potassium voltage-gated channel subfamily H member 2 Ligand (1r,5r)-30-oxo-19-oxa-2,6,10,12-tetraazahexacyclo[18.6.2.1^{2,5}.1^{14,18}.0^{8, 12}.0^{23,27}]triaconta-8,10,14(29),15,17,20(28),21,23(27)-octaene-17-carbonitri Le (structural Mix) Superfamily Class Class 1096
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAMM00306228 CHEMBL2111612 Bioactive
4-[(1S)-1-amino-1-(3-methylimidazol-4-yl)ethyl]-2-[3-[(3R)-3-ethyl-1-methyl-2-oxoazepan-3-yl]phenoxy]benzonitrile CFAMM00306227 CHEMBL450336 Bioactive
4-[(1S)-1-amino-1-(3-methylimidazol-4-yl)ethyl]-2-[3-[(3R)-3-(cyclopropylmethyl)-1-methyl-2-oxoazepan-3-yl]phenoxy]benzonitrile CFAMM00306226 CHEMBL316673 Bioactive
SureCN7671603 CFAMM00306232 CHEMBL318626 Bioactive
4-[(1S)-1-amino-1-(3-methylimidazol-4-yl)ethyl]-2-[3-[(3S)-1-methyl-2-oxo-3-propylazepan-3-yl]phenoxy]benzonitrile CFAMM00306225 CHEMBL322435 Bioactive
4-[(1S)-1-amino-1-(3-methylimidazol-4-yl)ethyl]-2-[3-[(3R)-3-(2-cyclopropylethyl)-1-methyl-2-oxoazepan-3-yl]phenoxy]benzonitrile CFAMM00306231 CHEMBL99901 Bioactive
4-[(1S)-1-amino-1-(3-methylimidazol-4-yl)ethyl]-2-[3-[(3S)-3-butyl-1-methyl-2-oxoazepan-3-yl]phenoxy]benzonitrile CFAMM00306224 CHEMBL102293 Bioactive
AC1MQSAW CFAMM00306230 CHEMBL100526 Bioactive
2-[3-(3-ethyl-1-methyl-2-oxoazepan-3-yl)phenoxy]-4-[(3-methylimidazol-4-yl)methyl]benzonitrile CFAMM00306229 CHEMBL294888 Bioactive
2-[3-(3-ETHYL-1-METHYL-2-OXO-AZEPAN-3-YL)-PHENOXY]-4-[1-AMINO-1-(1-METHYL-1H-IMIDIZOL-5-YL)-ETHYL]-BENZONITRILE
CFAM Mol ID
External ID
Functional Category
Molecule Name
Statistics of CFAM Database
490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
How to cite our database
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
Last update by
2014.08.29
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Dr.
Chen Yuzong Deputy
Director of Center for Computational Science and Engineering All rights reserved.
