Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.
CFAM Family ID CFFBM38
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor AC1MQSAW family
No. of Seeds 14
No. of Other Members 0
Family Centroid CFAMM00306224
Functional Category Bioactive
Superfamily Potassium voltage-gated channel subfamily H member 2 Ligand (1r,5r)-30-oxo-19-oxa-2,6,10,12-tetraazahexacyclo[18.6.2.1^{2,5}.1^{14,18}.0^{8, 12}.0^{23,27}]triaconta-8,10,14(29),15,17,20(28),21,23(27)-octaene-17-carbonitri Le (structural Mix) Superfamily
Class Class 1096
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAMM00306224
CHEMBL102293
Bioactive
AC1MQSAW CFAMM00306230
CHEMBL100526
Bioactive
2-[3-(3-ethyl-1-methyl-2-oxoazepan-3-yl)phenoxy]-4-[(3-methylimidazol-4-yl)methyl]benzonitrile CFAMM00306229
CHEMBL294888
Bioactive
2-[3-(3-ETHYL-1-METHYL-2-OXO-AZEPAN-3-YL)-PHENOXY]-4-[1-AMINO-1-(1-METHYL-1H-IMIDIZOL-5-YL)-ETHYL]-BENZONITRILE CFAMM00306228
CHEMBL2111612
Bioactive
4-[(1S)-1-amino-1-(3-methylimidazol-4-yl)ethyl]-2-[3-[(3R)-3-ethyl-1-methyl-2-oxoazepan-3-yl]phenoxy]benzonitrile CFAMM00306227
CHEMBL450336
Bioactive
4-[(1S)-1-amino-1-(3-methylimidazol-4-yl)ethyl]-2-[3-[(3R)-3-(cyclopropylmethyl)-1-methyl-2-oxoazepan-3-yl]phenoxy]benzonitrile CFAMM00306226
CHEMBL316673
Bioactive
SureCN7671603 CFAMM00306232
CHEMBL318626
Bioactive
4-[(1S)-1-amino-1-(3-methylimidazol-4-yl)ethyl]-2-[3-[(3S)-1-methyl-2-oxo-3-propylazepan-3-yl]phenoxy]benzonitrile CFAMM00306225
CHEMBL322435
Bioactive
4-[(1S)-1-amino-1-(3-methylimidazol-4-yl)ethyl]-2-[3-[(3R)-3-(2-cyclopropylethyl)-1-methyl-2-oxoazepan-3-yl]phenoxy]benzonitrile CFAMM00306231
CHEMBL99901
Bioactive
4-[(1S)-1-amino-1-(3-methylimidazol-4-yl)ethyl]-2-[3-[(3S)-3-butyl-1-methyl-2-oxoazepan-3-yl]phenoxy]benzonitrile
CFAM Mol ID
External ID
Functional Category
Molecule Name
Statistics of CFAM Database
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
How to cite our database
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
Last update by
2014.08.29
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Dr.
Chen Yuzong
Deputy
Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore
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