CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3838
Family Name Leukotriene B4 receptor 1 ligand SureCN8987110 family
No. of Seeds 8 No. of Other Members 20
Family Centroid CFAMM00351048 Functional Category Bioactive
Superfamily Trypsin-1 and Prothrombin Binder Superfamily 4
Class Class 224

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Leukotriene B4 receptor 1 Ligand SB-209247 Family 7 24
Leukotriene B4 receptor 1 Ligand SB-201993 Family 5 13
Metabotropic glutamate receptor 5 Ligand 2-(3-chlorobenzyloxy)... 2 6
Metabotropic glutamate receptor 1 Ligand JNJ-16259685 Family 3 20
Prostaglandin E2 receptor EP1 subtype Ligand GSK-345931A Family 5 14
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Endothelin-1 receptor and Endothelin B receptor ligand (5S,6R,... 15 28
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 10 4
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
Cysteinyl leukotriene receptor 1 ligand SureCN9053715 family 2 11
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 30
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 3
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
Leukotriene B4 receptor 1 ligand SureCN8987047 family 4 3
Arachidonate 5-lipoxygenase inhibitor (2E)-2-[2-butyl-1-[4-(qu... 1 12
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 2 13
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 16 5
Somatostatin receptor type 2 ligand SureCN4313450 family 2 25
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Cysteinyl leukotriene receptor 1 and Peripheral myelin protein... 1 1
Cysteinyl leukotriene receptor 1 ligand SureCN7008285 family 12 97
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 12 3
Peroxisome proliferator-activated receptor delta and Peroxisom... 22 1
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 4 4
Peroxisome proliferator-activated receptor gamma and Peroxisom... 9 2
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4
Transient receptor potential cation channel subfamily V member... 54 12
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 19 11
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[[4... 7 4
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 3 5
Disintegrin and metalloproteinase domain-containing protein 17... 8 0
Cysteinyl leukotriene receptor 1 ligand 4-oxo-7-[[3-(quinolin-... 4 17
Prothrombin and Trypsin-1 inhibitor AGN-PC-074I4I family 3 1
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Prothrombin inhibitor AGN-PC-074I2Z family 2 1
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (4R,... 2 0
Dipeptidyl peptidase 4 inhibitor 2-[3-(aminomethyl)-4-(4-fluor... 3 0
DNA polymerase beta and Microtubule-associated protein tau inh... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00351054 CHEMBL137303 Bioactive SureCN9292063
CFAMM00351047 CHEMBL137104 Bioactive SureCN8987390
CFAMM00351046 CHEMBL136991 Bioactive SureCN8987011
CFAMM00351038 CHEMBL342416 Bioactive SureCN8987009
CFAMM00351030 CHEMBL136960 Bioactive SureCN8986967
CFAMM00351043 CHEMBL137472 Bioactive SureCN8987045
CFAMM00351056 CHEMBL137494 Bioactive SureCN8986968
CFAMM00351048 CHEMBL137247 Bioactive SureCN8987110

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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