CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3843
Family Name Sigma non-opioid intracellular receptor 1 and D(2) dopamine receptor ligand SureCN467014 family
No. of Seeds 18 No. of Other Members 4
Family Centroid CFAMM00351099 Functional Category Bioactive
Superfamily Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21947 Superfamily
Class Class 48

Cousin Family NamesSeedsMembers
Serotonin re-uptake inhibitor tetralin derivative Sertraline f... 12 118
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Sibu... 7 127
Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21... 16 89
5-hydroxytryptamine receptor 2C Ligand Lorcaserin Family 8 38
Tumor necrosis factor Inhibitor Talactoferrin Alfa Family 26 131
Zicronapine family 43 62
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 10 52
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 3 7
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 6 7
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Sigma non-opioid intracellular receptor 1 ligand NCI60_038428 ... 5 9
Sigma non-opioid intracellular receptor 1 ligand 1-[2-(3,4-dic... 8 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 5 6
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 0
Transporter and Sodium-dependent dopamine transporter inhibito... 3 0
Transporter and Sodium-dependent serotonin transporter inhibit... 4 8
Sodium-dependent dopamine transporter inhibitor N-[[(1S,3S,4R,... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 3
Sodium-dependent dopamine transporter and Sodium-dependent nor... 3 1
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
D(1A) dopamine receptor and D(2) dopamine receptor ligand A314... 3 1
Sigma non-opioid intracellular receptor 1 ligand NCI60_039912 ... 2 0
D(2) dopamine receptor and D(1A) dopamine receptor ligand AGN-... 2 1
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 6
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00351092 CHEMBL71049 Bioactive 2-(4,5-dichloro-2-iodophenyl)-N-methyl-N-(2-pyrrolidin-1-ylethyl)ethanamine
CFAMM00351105 CHEMBL70861 Bioactive AC1LBJ42
CFAMM00351098 CHEMBL343790 Bioactive (2R)-1-[2-(3,4-dichlorophenyl)ethyl]-2-(pyrrolidin-1-ylmethyl)pyrrolidine
CFAMM00351091 CHEMBL342223 Bioactive SureCN466865
CFAMM00351104 CHEMBL141945 Bioactive AGN-PC-003SR2
CFAMM00351097 CHEMBL136981 Bioactive 1-[2-(3,4-Dichlorophenyl)ethyl]-3-(1-pyrrolidinyl)azepane
CFAMM00351090 CHEMBL142336 Bioactive AGN-PC-003SQW
CFAMM00351103 CHEMBL422834 Bioactive (2R)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-1-pyrrolidin-1-ylpropan-2-amine
CFAMM00351096 CHEMBL358109 Bioactive AC1LBJ0W
CFAMM00351089 CHEMBL337818 Bioactive (2S)-1-[2-(3,4-dichlorophenyl)ethyl]-2-(pyrrolidin-1-ylmethyl)pyrrolidine
CFAMM00351095 CHEMBL142596 Bioactive 1-Pyrrolidineethanamine, N-[2-(3-chlorophenyl)ethyl]-N-methyl-
CFAMM00351101 CHEMBL347514 Bioactive SureCN7401434
CFAMM00351107 CHEMBL422826 Bioactive N-[2-(3,4-dichlorophenyl)ethyl]-N-(2-pyrrolidin-1-ylethyl)prop-2-en-1-amine
CFAMM00351100 CHEMBL143178 Bioactive AGN-PC-003SR6
CFAMM00351099 CHEMBL141501 Bioactive SureCN467014

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48712 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543