CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3855
Family Name Leukotriene B4 receptor 1 ligand SureCN8987047 family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00351184 Functional Category Bioactive
Superfamily Endothelin-1 receptor and Endothelin B receptor Binder Superfamily
Class Class 3074

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Leukotriene B4 receptor 1 Ligand SB-201993 Family 5 13
Metabotropic glutamate receptor 1 Ligand JNJ-16259685 Family 3 20
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 4 5
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Endothelin-1 receptor and Endothelin B receptor ligand (5S,6R,... 15 28
Endothelin-1 receptor and Endothelin B receptor ligand (5S,6R,... 23 8
Endothelin-1 receptor and Endothelin B receptor ligand 3-(1,3-... 1 1
Endothelin-1 receptor and Endothelin B receptor ligand SureCN1... 3 16
Leukotriene B4 receptor 1 ligand AGN-PC-04XM3V family 3 10
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
Cysteinyl leukotriene receptor 1 ligand SureCN9053715 family 2 11
Insulin-like growth factor-binding protein 4 and Insulin-like ... 4 44
Leukotriene B4 receptor 1 ligand SureCN8987110 family 8 20
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(1,3-... 2 9
Cellular tumor antigen p53 inhibitor CHEMBL1395699 family 1 30
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 7 4
Arachidonate 5-lipoxygenase inhibitor (2E)-2-[2-butyl-1-[4-(qu... 1 12
Butyrylcholinesterase and Acetylcholinesterase inhibitor AGN-P... 9 24
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 16 5
Sodium-dependent serotonin transporter inhibitor (4S)-4-[4-[(2... 1 3
Cysteinyl leukotriene receptor 1 and Peripheral myelin protein... 1 1
Corticotropin-releasing factor receptor 1 ligand 2-(2-ethyl-4,... 4 9
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 12 3
Peroxisome proliferator-activated receptor delta and Peroxisom... 22 1
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 4 4
Peroxisome proliferator-activated receptor gamma and Peroxisom... 9 2
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 2
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[[4... 7 4
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 3 5
Disintegrin and metalloproteinase domain-containing protein 17... 8 0
Insulin-like growth factor-binding protein 3 inhibitor (1E)-1-... 2 0
Prothrombin and Trypsin-1 inhibitor AGN-PC-074I4I family 3 1
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Adenosine receptor A1 ligand BAS 00727702 family 1 4
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (4R,... 2 0
Beta-lactamase and Muscleblind-like protein 1 inhibitor 2,3-Bi... 1 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00351180 CHEMBL137330 Bioactive SureCN6757553
CFAMM00351186 CHEMBL137759 Bioactive SureCN8987320
CFAMM00351184 CHEMBL137341 Bioactive SureCN8987047
CFAMM00351182 CHEMBL137074 Bioactive SureCN9291839

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27272 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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