CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM38757
Family Name Nuclear receptor ROR-gamma and Retinal dehydrogenase 1 ligand CHEMBL1499966 family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00512308 Functional Category Bioactive with Natural Product
Superfamily Retinal dehydrogenase 1 and Nuclear receptor ROR-gamma Binder Superfamily 16
Class Class 4891

Cousin Family NamesSeedsMembers
Cytochrome P450 1B1 Inhibitor N-(2,4-dimethoxy-phenyl)-3,5-dim... 1 110
Estrogen receptor beta Ligand 5,7-dihydroxy-3-phenyl-3h-quinaz... 2 17
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Aldose reductase Inhibitor 7-hydroxy-6-nitro-2-phenyl-chromen-... 2 17
Gamma-aminobutyric acid receptor Ligand 2-(2-amino-phenyl)-6-m... 4 23
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 4 65
Acetylcholinesterase and Cholinesterase inhibitor [3-[4-(3,4-d... 3 18
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 9
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 7
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 inhibi... 1 23
Tyrosine-protein kinase ABL1 inhibitor N-(4-bromophenyl)-2-(5-... 1 3
Malate dehydrogenase, mitochondrial and Lactate dehydrogenase ... 1 1
Estrogen receptor beta and Estrogen receptor ligand 8-amino-3-... 2 2
Quinolines and Derivatives Metabolite Gravacridonediol Family 9 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00512306 CHEMBL1946828 Bioactive (2Z)-2-[[4-(dimethylamino)phenyl]methylidene]-6-hydroxy-1-benzofuran-3-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27518 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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