CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM388
Family Name Motilin receptor and Growth hormone secretagogue receptor type 1 ligand 4-butyl-N-[3-[(5-methyl-1H-imidazol-4-yl)methyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]benzenesulfonamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00311010 Functional Category Bioactive
Superfamily Alpha-1A adrenergic receptor Ligand A-315456 Superfamily
Class Class 2000

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Farnesyltransferase beta subunit, putative Inhibitor BMS214662... 11 65
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... 6 3
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Protein farnesyltransferase subunit beta Inhibitor BMS-316810 ... 11 18
Farnesyltransferase beta subunit, putative and Protein farnesy... 12 4
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... 25 10
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 4
Macrophage colony-stimulating factor 1 receptor ligand SureCN1... 28 9
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Protein farnesyltransferase alpha subunit and Protein farnesyl... 5 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
5-hydroxytryptamine receptor 2B ligand SureCN1299213 family 3 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 1
A disintegrin and metalloproteinase with thrombospondin motifs... 1 0
Histone deacetylase 1 inhibitor (7S)-7-(5-naphthalen-2-yl-1H-i... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00311010 CHEMBL1079186 Bioactive 4-butyl-N-[3-[(5-methyl-1H-imidazol-4-yl)methyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]benzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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