CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM38915
Family Name Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 inhibitor 1-(8-tert-butyl-1,4,4-trimethyl-2,3-dihydroquinolin-6-yl)pentan-1-one family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00512585 Functional Category Bioactive
Superfamily Acetylcholinesterase and Niemann-Pick C1 protein Binder Superfamily
Class Class 2521

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
K-604 family 4 71
Pan-DAC Inhibitor AR-42 Family 21 153
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Fumarate reductase flavoprotein subunit Inhibitor 2-heptyl-4-h... 3 16
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 13
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 7
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor AGN-PC-006C4... 1 1
Acetylcholinesterase inhibitor CHEMBL1651130 family 2 3
Amyloid beta A4 protein inhibitor AGN-PC-08WTQK family 1 3
Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis... 2 1
Histamine H3 receptor ligand SureCN3058680 family 4 0
Glucose-dependent insulinotropic receptor ligand AGN-PC-04UO8L... 2 2
(8-methyl-6-oxo-1,2,3a,4,5,6-hexahydro-3H-3,10b-diazaacephenan... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00512585 CHEMBL15039 Bioactive 1-(8-tert-butyl-1,4,4-trimethyl-2,3-dihydroquinolin-6-yl)pentan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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