CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM38963
Family Name Lysine-specific demethylase 4E and Lethal(3)malignant brain tumor-like protein 1 inhibitor CHEMBL1505256 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00512664 Functional Category Bioactive
Superfamily Lethal(3)malignant brain tumor-like protein 1 and Muscleblind-like protein 1 Binder Superfamily
Class Class 1022

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Triprolidine Family 19 316
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 22
NF-kappa-B Inhibitor 2-nitro-n-(quinolin-8-yl)benzenesulfonami... 2 3
Hepatocyte growth factor receptor Ligand 1-benzyl-1h-pyrrolo[3... 2 16
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 1 3
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Trypsin Inhibitor 4-(5-nitro-indol-1-ylmethyl)-benzamidine Family 2 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 3
Metabotropic glutamate receptor 5 ligand AGN-PC-0A9SQ6 family 3 0
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 2 2


External ID

Functional Category

Molecule Name

CFAMM00512665 CHEMBL78977 Bioactive 1-[2-(4-methyl-1,4-diazepan-1-yl)ethyl]-6-nitroindole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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