CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3911
Family Name Neutrophil elastase inhibitor benzyl 2-[2,4,8-trioxo-7-[2-oxo-2-[(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)amino]ethyl]-6-phenyl-1H-pyrido[3,4-d]pyrimidin-3-yl]acetate family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00351640 Functional Category Bioactive
Superfamily Neutrophil elastase and Chymotrypsin-C Binder Superfamily
Class Class 3304

Cousin Family NamesSeedsMembers
Elagolix family 43 98
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
Neutrophil elastase inhibitor benzyl N-[2-(4-aminophenyl)-6-ox... 4 23
Neutrophil elastase inhibitor SureCN7276766 family 3 6
Neutrophil elastase inhibitor SureCN7276506 family 2 7
Neutrophil elastase and Chymotrypsin-C inhibitor benzyl N-[6-(... 3 6
Neutrophil elastase inhibitor benzyl N-[(2S)-1-[(2S)-2-[[(3S)-... 4 0
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 3
Gonadotropin-releasing hormone receptor ligand 5-(2-chloro-3-m... 5 0
Neutrophil elastase inhibitor SureCN7273831 family 2 2
Protease inhibitor AC1O54RX family 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00351640 CHEMBL13753 Bioactive benzyl 2-[2,4,8-trioxo-7-[2-oxo-2-[(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)amino]ethyl]-6-phenyl-1H-pyrido[3,4-d]pyrimidin-3-yl]acetate
CFAMM00351638 CHEMBL14121 Bioactive SureCN7415630

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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