CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM396
Family Name Deoxycytidine kinase inhibitor AGN-PC-07Z9C8 family
No. of Seeds 5 No. of Other Members 3
Family Centroid CFAMM00311053 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 Inhibitor Pamapimod Superfamily
Class Class 1208

Cousin Family NamesSeedsMembers
Endothelin B receptor and Endothelin-1 receptor ligand pyrimid... 22 180
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
SB1518 family 7 103
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 2 3
5-hydroxytryptamine receptor 1A Ligand CP-293019 Family 9 24
Deoxycytidine kinase inhibitor AGN-PC-07Z9GO family 10 2
Deoxycytidine kinase inhibitor 2-[1-[6-(2-chlorophenoxy)pyrimi... 2 3
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 1 7
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 4 2
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 6
Adenosine kinase inhibitor 5-[3-(4-methoxyphenyl)propyl]-6-[2-... 2 11
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 8
Dihydrofolate reductase inhibitor AC1LA5HU family 8 4
Lethal factor and Dual specificity protein kinase CLK4 inhibit... 1 3
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0
Endothelin-1 receptor and Endothelin B receptor ligand 6-[2-(5... 3 1
Endothelin-1 receptor and Endothelin B receptor ligand 6-[2-(5... 7 0
Endothelin-1 receptor and Endothelin B receptor ligand N-(benz... 4 0
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 1 0
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 5 12
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 3
P2X purinoceptor 3 and P2X purinoceptor 2 inhibitor 2-[[4-amin... 10 9
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 2
Glucose-dependent insulinotropic receptor ligand tert-butyl 4-... 1 1
Alpha-1A adrenergic receptor and D(2) dopamine receptor ligand... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00311054 CHEMBL1081350 Bioactive AGN-PC-07Z9DE
CFAMM00311053 CHEMBL1079603 Bioactive AGN-PC-07Z9C8
CFAMM00311050 CHEMBL1079379 Bioactive SureCN310854
CFAMM00311056 CHEMBL1079601 Bioactive AGN-PC-07Z9C6
CFAMM00311055 CHEMBL1079735 Bioactive 2-[1-[6-(2-ethylphenoxy)pyrimidin-4-yl]piperidin-4-yl]oxy-5-fluoropyrimidin-4-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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