CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM3961
Family Name Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-044LPE family
No. of Seeds 6 No. of Other Members 7
Family Centroid CFAMM00307207 Functional Category Bioactive
Superfamily Stromelysin-1 and Neutrophil collagenase Binder Superfamily 2
Class Class 3081

Cousin Family NamesSeedsMembers
ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase I... 2 2
Suppressor of tumorigenicity 14 protein and Prothrombin Inhibi... 4 126
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Suppressor of tumorigenicity 14 protein Inhibitor 3-tapap Family 15 39
Disintegrin and metalloproteinase domain-containing protein 17... 7 39
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 7 8
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Trypsin Inhibitor Benzamidrazone Analogue Family 16 6
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 11
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 6
72 kDa type IV collagenase and Neutrophil collagenase inhibito... 8 4
Cathepsin L1 and Cathepsin B inhibitor (2S)-3-methyl-N-[(2S)-4... 7 24
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 6 8
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 1
Disintegrin and metalloproteinase domain-containing protein 17... 6 5
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
Replication protein E1 inhibitor AC1LAK2U family 3 10
B1 bradykinin receptor ligand SureCN13936521 family 19 4
Poly [ADP-ribose] polymerase 1 inhibitor SureCN2769748 family 1 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 10 1
Cathepsin K and Cathepsin L1 inhibitor N-[1-(cyanomethylcarbam... 2 0
B1 bradykinin receptor and B2 bradykinin receptor ligand SureC... 3 0
Neutrophil collagenase and Collagenase 3 inhibitor (2R)-2-[2-a... 1 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 7 1
Microbial collagenase inhibitor AGN-PC-00F1J7 family 4 2
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-2-... 2 0
Calpain-1 catalytic subunit inhibitor N-[(2S)-4-[2-[[4-[(4-ace... 1 0
Endothelin-converting enzyme 1 and Angiotensin-converting enzy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00351965 CHEMBL56621 Bioactive (3R)-2-(4-benzoylphenyl)sulfonyl-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamide
CFAMM00351964 CHEMBL299664 Bioactive (3R)-2-[4-(4-chlorophenyl)phenyl]sulfonyl-N-hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxamide
CFAMM00351970 CHEMBL293044 Bioactive (3R)-N-hydroxy-2-(4-phenylphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxamide
CFAMM00351968 CHEMBL422105 Bioactive AGN-PC-03SZ9Z

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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