CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand SureCN1408120 family
No. of Seeds 4 No. of Other Members 16
Family Centroid CFAMM00311176 Functional Category Bioactive
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Binder Superfamily 9
Class Class 3082

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Type-2 angiotensin II receptor Ligand SC-50560 Family 3 84
D(3) dopamine receptor and D(2) dopamine receptor ligand (1S,5... 3 4
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-met... 7 12
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 3 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 17 10
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 4-met... 11 12
Somatostatin receptor type 5 and Somatostatin receptor type 2 ... 6 3
Mitogen-activated protein kinase 14 inhibitor imidazole 81 family 2 1
Metabotropic glutamate receptor 2 ligand 3-(cyclopropylmethyl)... 1 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 2 0
D(3) dopamine receptor and Muscarinic acetylcholine receptor M... 8 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3-[2-... 2 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 1-met... 2 0
Type-1 angiotensin II receptor ligand SureCN9402249 family 4 7
Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-prote... 2 26


External ID

Functional Category

Molecule Name

CFAMM00311169 CHEMBL1079475 Bioactive (1S,5R)-3-[3-[(4-methyl-5-pyrimidin-5-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane
CFAMM00311166 CHEMBL1258034 Bioactive AGN-PC-087TT1
CFAMM00311176 CHEMBL1081867 Bioactive SureCN1408120
CFAMM00311165 CHEMBL1081686 Bioactive (1S,5R)-3-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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