CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM403
Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand (1S,5R)-3-[3-[[4-methyl-5-(6-methylpyridin-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00311168 Functional Category Bioactive
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Binder Superfamily 9
Class Class 3082

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Hepatocyte growth factor receptor Ligand SGX523 Family 1 15
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 14 4
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 16
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-met... 7 12
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 3 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Type-1B angiotensin II receptor ligand SureCN683399 family 3 0
Glycogen synthase kinase-3 beta and Dual specificity protein k... 4 5
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Somatostatin receptor type 5 and Somatostatin receptor type 2 ... 6 3
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 1 0
Tyrosine-protein kinase Mer and Tyrosine-protein kinase recept... 5 3
TGF-beta receptor type-1 and TGF-beta receptor type-2 ligand S... 2 2
Mitogen-activated protein kinase 14 inhibitor imidazole 81 family 2 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Metabotropic glutamate receptor 2 ligand 3-(cyclopropylmethyl)... 1 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 2 0
D(3) dopamine receptor and Muscarinic acetylcholine receptor M... 8 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 1-met... 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[6-... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23192 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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