CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4039
Family Name 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 7 ligand N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-3-sulfonamide family
No. of Seeds 2 No. of Other Members 15
Family Centroid CFAMM00286333 Functional Category Bioactive
Superfamily Growth hormone secretagogue receptor type 1 and 5-hydroxytryptamine receptor 7 Binder Superfamily
Class Class 2393

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
72 kDa type IV collagenase and Interstitial collagenase Inhibi... 5 81
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Family 2 9
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 11 49
Apricoxib family 8 77
Indeglitazar family 3 39
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
D(2) dopamine receptor Ligand SLV-314 Family 19 69
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-m... 2 12
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Prostaglandin G/H synthase 2 Inhibitor 5-methoxy-2-(4-(methyls... 3 12
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
5-hydroxytryptamine receptor 6 ligand N-[3-[[(2R)-1-methylpyrr... 6 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 5
Cannabinoid receptor 2 ligand AGN-PC-09M5M9 family 1 0
5-hydroxytryptamine receptor 6 ligand SureCN5502542 family 4 2
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 1 8
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(2-... 3 3
5-hydroxytryptamine receptor 6 ligand 1-[9-(benzenesulfonyl)-6... 11 2
5-hydroxytryptamine receptor 6 ligand SureCN5498885 family 5 4
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Disintegrin and metalloproteinase domain-containing protein 17... 44 12
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 2 0
Sodium-dependent serotonin transporter inhibitor SureCN7536104... 6 2
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 3 0
Collagenase 3 and Interstitial collagenase inhibitor (2R,5R)-N... 4 1
5-hydroxytryptamine receptor 6 ligand SureCN5253197 family 4 2
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
5-hydroxytryptamine receptor 6 ligand 9-(4-methoxyphenyl)sulfo... 1 0
5-hydroxytryptamine receptor 6 ligand 1-(2-bromo-4-methoxyphen... 2 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Growth hormone secretagogue receptor type 1 ligand SureCN48016... 1 0
Growth hormone secretagogue receptor type 1 ligand SureCN47983... 4 9
Growth hormone secretagogue receptor type 1 ligand SureCN47965... 3 1
Orexin receptor type 2 and Orexin receptor type 1 ligand N-eth... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-[1-... 1 0
D(2) dopamine receptor and D(4) dopamine receptor ligand AGN-P... 1 0
Neutrophil collagenase and Stromelysin-1 inhibitor (3R)-N-hydr... 2 0
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 5 13
D(2) dopamine receptor ligand SureCN10575660 family 1 1
5-hydroxytryptamine receptor 6 ligand 1-[9-(2,5-dimethoxypheny... 2 0
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 3 3
Oxytocin receptor and Vasopressin V1a receptor ligand 4-methox... 9 8
Protein kinase C theta type and Protein kinase C delta type in... 10 7
5-hydroxytryptamine receptor 6 and Cytochrome P450 3A4 ligand ... 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 9 0
DNA-(apurinic or apyrimidinic site) lyase and Alkaline phospha... 1 2
Prothrombin inhibitor N-[(2S)-3-(4-aminophenyl)-1-[4-(2-fluoro... 7 4
5-hydroxytryptamine receptor 6 ligand SureCN5366229 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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