CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand 2-methyl-5-[4-methyl-5-[3-(1-phenyl-3-azabicyclo[3.1.0]hexan-3-yl)propylsulfanyl]-1,2,4-triazol-3-yl]quinoline family
No. of Seeds 7 No. of Other Members 12
Family Centroid CFAMM00311164 Functional Category Bioactive
Superfamily D(3) dopamine receptor and Beta-lactamase Binder Superfamily
Class Class 1190

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Type-1 angiotensin II receptor Ligand Forasartan Family 3 253
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 14 4
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 16
D(3) dopamine receptor and D(2) dopamine receptor ligand (1S,5... 3 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Somatostatin receptor type 5 and Somatostatin receptor type 2 ... 6 3
D(3) dopamine receptor and Muscarinic acetylcholine receptor M... 8 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 1-met... 2 0
D(3) dopamine receptor and Potassium voltage-gated channel sub... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[6-... 3 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3-[2-... 9 0


External ID

Functional Category

Molecule Name

CFAMM00311205 CHEMBL1079497 Bioactive AGN-PC-00A4UI
CFAMM00311212 CHEMBL1080117 Bioactive 5-[5-[3-[1-(4-chlorophenyl)-3-azabicyclo[3.1.0]hexan-3-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-2-methylquinoline
CFAMM00311221 CHEMBL1080165 Bioactive 5-[5-[3-[(1S,5R)-1-(4-bromophenyl)-3-azabicyclo[3.1.0]hexan-3-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-2-methylquinoline

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



70847 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543