CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM40514
Family Name Heat shock protein HSP 90-alpha inhibitor 4-[2-Chloro-6-(4,4,4-Trifluorobutoxy)phenyl]-6-Methylpyrimidin-2-Amine family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00515692 Functional Category Bioactive with Natural Product
Superfamily Heat shock protein HSP 90-alpha and Protein kinase C alpha type Binder Superfamily
Class Class 2955

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor 5-(4-methoxypheno... 5 61
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Cathepsin S and Cathepsin K inhibitor AGN-PC-088VBO family 3 11
Dihydrofolate reductase inhibitor 7-(2-ethoxynaphthalen-1-yl)-... 3 2
Transient receptor potential cation channel subfamily V member... 2 4
Xanthine dehydrogenase/oxidase inhibitor 5-(2-amino-4-oxo-1H-p... 8 30
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 2
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 6
Epidermal growth factor receptor ligand 4-Anilinoquinazoline d... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00515692 CHEMBL1738804 Bioactive 4-[2-Chloro-6-(4,4,4-Trifluorobutoxy)phenyl]-6-Methylpyrimidin-2-Amine
CFAMM00515690 CHEMBL1774833 Bioactive AGN-PC-00IQHE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26400 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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