CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM40630
Family Name Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3 alpha inhibitor 4-arylmaleimide deriv. 6o family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00515902 Functional Category Bioactive
Superfamily Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3 alpha Binder Superfamily 7
Class Class 516

Cousin Family NamesSeedsMembers
High affinity nerve growth factor receptor and RAF proto-oncog... 3 29
Epidermal growth factor receptor Ligand 4-acrylamido-n-(3-brom... 2 20
Macrophage migration inhibitory factor Inhibitor 2-(4-hydroxys... 8 19
Delta-type opioid receptor and Kappa-type opioid receptor liga... 15 6
Serine/threonine-protein kinase B-raf inhibitor 5,6-bis(3-hydr... 2 2


External ID

Functional Category

Molecule Name

CFAMM00515903 CHEMBL158559 Bioactive 3-(3-hydroxyanilino)-4-(3-nitrophenyl)pyrrole-2,5-dione
CFAMM00515902 CHEMBL350435 Bioactive 4-arylmaleimide deriv. 6o
CFAMM00515906 CHEMBL347419 Bioactive 4-arylmaleimide deriv. 6v
CFAMM00515905 CHEMBL160937 Bioactive SB-390527
CFAMM00515904 CHEMBL155931 Bioactive 3-(3-hydroxyanilino)-4-(2-nitrophenyl)pyrrole-2,5-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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