CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4067
Family Name Mu-type opioid receptor and Kappa-type opioid receptor ligand SureCN12555346 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00352762 Functional Category Bioactive
Superfamily Cathepsin S and Cathepsin L1 Binder Superfamily
Class Class 3305

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Prothrombin Inhibitor Ximelegatran Family 8 157
Neuromedin-K receptor Ligand SB222200 Family 17 235
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Glutamate receptor AMPA subtype Ligand CX-516 Family 9 24
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
Branched-chain-amino-acid aminotransferase, cytosolic Inhibito... 1 2
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
Transient receptor potential cation channel subfamily V member... 6 23
D(4) dopamine receptor Ligand ABT-670 Family 4 14
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Glutamate receptor 1 Ligand Piriqualone Family 8 67
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 27
Endothelin B receptor Ligand IRL-2500 Family 34 87
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 4 21
Histamine H3 receptor ligand AGN-PC-04YWRD family 5 13
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 36
Prelamin-A/C and Pyruvate kinase PKM inhibitor CHEMBL1481187 f... 1 7
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 5 5
Neuropeptide Y receptor type 5 ligand 2-indol-1-yl-N-[4-[(prop... 7 6
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 5 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 2 3
Glutamate receptor ionotropic, NMDA 2B ligand N-[3-[2-(4-benzy... 2 0
Cannabinoid receptor 1 ligand N-(cyclobutylmethyl)-3-[[4-(meth... 1 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 6-(b... 5 5
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 3
Platelet-activating factor receptor ligand (4R)-N-(3-benzoylph... 2 1
Coagulation factor X and Trypsin-1 inhibitor SureCN6166035 family 1 2
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 10 14
C-X-C chemokine receptor type 3 ligand AGN-PC-07ZH3V family 1 1
Oxytocin receptor ligand 3-[(1R,3S,4S)-7,7-dimethyl-4-(spiro[1... 2 1
Presenilin-1 and Presenilin-2 inhibitor AGN-PC-075DUF family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00352762 CHEMBL138653 Bioactive SureCN12555346

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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