CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4080
Family Name Protease and Capsid scaffolding protein inhibitor AC1LAC7K family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00352821 Functional Category Bioactive
Superfamily Protease and Capsid scaffolding protein Binder Superfamily
Class Class 1257

Cousin Family NamesSeedsMembers
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing... 3 16
Prothrombin Inhibitor RWJ-50353 Family 11 95
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 2 5
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Prothrombin inhibitor (2S)-N-[(4-carbamimidoyl-1,3-thiazol-2-y... 3 2
Vascular endothelial growth factor receptor 2 ligand F2096-067... 2 1
Trypsin-1 and Prothrombin inhibitor (6S,8aS)-N-[(2S)-5-(diamin... 1 1
Prothrombin and Cationic trypsin inhibitor 2-ketobenzothiazole... 3 3
Prothrombin inhibitor methyl 2-[(2S)-5-(diaminomethylideneamin... 4 2
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-phenyl-1,3-t... 3 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 3
Suppressor of tumorigenicity 14 protein and Serine protease he... 6 0
Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-... 2 1
Capsid scaffolding protein inhibitor AC1LAC7W family 2 2
Prothrombin and Cationic trypsin inhibitor 2-ketobenzothiazole... 1 0
Cationic trypsin and Prothrombin inhibitor (2S)-N-[1-(1,3-benz... 1 0
Calcitonin gene-related peptide type 1 receptor ligand N-[(2R)... 1 0
RAC-alpha serine/threonine-protein kinase and Mast/stem cell g... 2 0
Prothrombin and Trypsin-1 inhibitor (2S)-1-[(2R)-2-amino-3,3-d... 1 3
Granzyme B inhibitor CHEMBL436855 family 2 2


External ID

Functional Category

Molecule Name

CFAMM00352819 CHEMBL344656 Bioactive AC1LAC6Z
CFAMM00352821 CHEMBL138762 Bioactive AC1LAC7K

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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