CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4086
Family Name Coagulation factor X and Prothrombin inhibitor 2-(3-amino-1,2-benzoxazol-5-yl)-N-[2-fluoro-4-(2-sulfamoylphenyl)phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide family
No. of Seeds 5 No. of Other Members 3
Family Centroid CFAMM00352871 Functional Category Bioactive
Superfamily Coagulation factor X and Prothrombin Inhibitor BMS-740808 Superfamily
Class Class 2345

Cousin Family NamesSeedsMembers
Coagulation factor X Inhibitor Apixaban Family 34 52
Coagulation factor IX and Coagulation factor X Inhibitor Razax... 22 34
Coagulation factor X and Prothrombin Inhibitor BMS-740808 Family 64 8
Coagulation factor X and Prothrombin inhibitor 1-(3-amino-1,2-... 4 0
Coagulation factor X inhibitor AGN-PC-00FGDC family 11 5
Coagulation factor X inhibitor AGN-PC-046RMH family 5 0
Coagulation factor X inhibitor 1-(4-methoxyphenyl)-7-oxo-6-[4-... 5 0
Coagulation factor X and Prothrombin inhibitor 1-(4-methoxyphe... 8 0
Coagulation factor X inhibitor AGN-PC-046QD2 family 6 0
Coagulation factor X and Prothrombin inhibitor 1-(3-amino-1,2-... 9 0
Coagulation factor X inhibitor 1-(3-amino-1,2-benzoxazol-5-yl)... 3 0
Coagulation factor X inhibitor SureCN5107814 family 6 0
Coagulation factor X inhibitor SureCN6603523 family 4 0
Coagulation factor X inhibitor 1-[2-(3-amino-1,2-benzoxazol-5-... 7 0
Coagulation factor X inhibitor AGN-PC-02YW2V family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00352868 CHEMBL554926 Bioactive AGN-PC-009XNJ
CFAMM00352866 CHEMBL138787 Bioactive pyrazole-based inhibitor, 23a
CFAMM00352872 CHEMBL428749 Bioactive AGN-PC-046RMB
CFAMM00352871 CHEMBL425512 Bioactive 2-(3-amino-1,2-benzoxazol-5-yl)-N-[2-fluoro-4-(2-sulfamoylphenyl)phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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