CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4108
Family Name 5-hydroxytryptamine receptor 1A and D(3) dopamine receptor ligand 8-[4-[[(2R)-5-fluoro-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-8-azaspiro[4.5]decane-7,9-dione family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00353003 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and Menin Binder Superfamily
Class Class 1062

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
Noradrenergic re-uptake Inhibitor Milnacipran Family 7 51
Peripheral carotid chemoreceptor Ligand Doxapram Family 4 36
Cytochrome P450 2D6 Inhibitor Glutethimide Family 1 1
Substance-P receptor Ligand Orvepitant Family 11 46
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Hemagglutinin Inhibitor Cl 385319 Family 18 101
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor Bexlosteride... 5 23
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Kappa-type opioid receptor ligand 6-[2-oxo-2-[(2S)-2-(pyrrolid... 6 4
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 18
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (2S... 16 24
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 7 3
Nociceptin receptor and Kappa-type opioid receptor ligand Pipe... 1 0
5-hydroxytryptamine receptor 1A ligand [(7S,8R)-7-(dipropylami... 4 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 3 1
5-hydroxytryptamine receptor 1A ligand 8-[4-[[(2R)-8-acetyl-5-... 1 0
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor 8-bromo-4-me... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00353004 CHEMBL139089 Bioactive 8-[4-[[(2R)-5-fluoro-1,2,3,4-tetrahydronaphthalen-2-yl]amino]butyl]-8-azaspiro[4.5]decane-7,9-dione
CFAMM00353003 CHEMBL138998 Bioactive 8-[4-[[(2R)-5-fluoro-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-8-azaspiro[4.5]decane-7,9-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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