CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM415
Family Name Deoxycytidine kinase inhibitor AGN-PC-07Z9B3 family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00311336 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform and Serine/threonine-protein kinase mTOR Binder Superfamily
Class Class 1154

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Interleukin-12 subunit alpha Inhibitor STA-5326 Family 2 51
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8 53
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 9 11
GDC-0349 family 44 77
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 6 64
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
Adenosine kinase inhibitor abt-702 family 14 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 9
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 7 1
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Adenosine kinase inhibitor 5-[3-(3-bromophenyl)propyl]-6-[2-(6... 3 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 6 11
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 2 3
Epidermal growth factor receptor ligand pyrido[4,3-d]pyrimidin... 11 0
DNA-(apurinic or apyrimidinic site) lyase and Neuropeptide S r... 1 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 10
Fatty-acid amide hydrolase 1 inhibitor 3-[(3S)-1-[4-(5-chlorot... 2 1
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-0A9RCZ family 7 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 1
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Serine/threonine-protein kinase Chk1 inhibitor 3-[5-[2-[(4-mor... 2 3
Serine/threonine-protein kinase Chk1 inhibitor 5-[5-(1-methylp... 3 2
Transient receptor potential cation channel subfamily V member... 4 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 9 0
Vascular endothelial growth factor receptor 2 ligand AC1NS6KN ... 4 5
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
Adenosine kinase inhibitor SureCN8248615 family 2 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 5 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00311337 CHEMBL226486 Bioactive 5-(1-benzothiophen-2-yl)-6-[2-(6-morpholin-4-ylpyridin-3-yl)ethynyl]pyrimidin-4-amine
CFAMM00311336 CHEMBL1079768 Bioactive AGN-PC-07Z9B3

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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