CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4168
Family Name Pol polyprotein inhibitor AC1LA9K7 family
No. of Seeds 7 No. of Other Members 23
Family Centroid CFAMM00353353 Functional Category Bioactive
Superfamily Pol polyprotein and Collagenase 3 Binder Superfamily
Class Class 3387

Cousin Family NamesSeedsMembers
G protein-activated inward rectifier potassium channel 4 ligan... 6 9
ATP-sensitive inward rectifier potassium channel 10 Ligand Gli... 1 2
Stromelysin-1 Inhibitor PG-530742 Family 4 23
D(2) dopamine receptor Ligand Rotigotine Patch Family 1 2
Neutrophil elastase Inhibitor Sivelestat Sodium Hydrate Family 2 2
5-hydroxytryptamine receptor Ligand Bay X3702 Family 3 12
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 2 55
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 2-[benz... 9 9
Beta-secretase 1 and Cathepsin D inhibitor 3ixj family 10 21
Beta-secretase 1 inhibitor SureCN8292705 family 7 6
Pol polyprotein inhibitor 2-[(2R,3S)-3-[[(2R)-3-(benzenesulfin... 15 15
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide, 8... 4 15
Pol polyprotein inhibitor morpholinone scaffold 1 family 5 29
Beta-secretase 1 and Beta-secretase 2 inhibitor SureCN5224847 ... 3 24
Integrin beta-3 and Integrin alpha-IIb inhibitor (2R)-2-(benze... 4 13
Pol polyprotein inhibitor benzyl (2S)-2-[[[(2S)-3-[cyclopentyl... 2 6
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Neutrophil collagenase and Stromelysin-1 inhibitor 7-[[(2S)-2-... 10 9
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R,4S)... 3 0
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Pol polyprotein inhibitor AC1NQUJL family 10 11
Pol polyprotein inhibitor AGN-PC-075V7I family 7 1
Beta-secretase 1 and Cathepsin B inhibitor N-[(2S)-1-[[(2S,3R)... 2 1
Beta-secretase 1 and Beta-secretase 2 inhibitor 3-(1,1-dioxoth... 6 2
Pol polyprotein inhibitor N-[2-Hydroxy-2-(8-Isopropyl-6,9-Diox... 7 6
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6429531 f... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 5 2
Carbonic anhydrase 2 and Carbonic anhydrase 9 inhibitor zinc;4... 4 0
Pol polyprotein inhibitor AC1LA9KP family 1 0
Beta-secretase 1 inhibitor N-[(2S,3R)-1-(3,5-difluorophenyl)-3... 5 5
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-acety... 6 7
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzo... 6 7
Carbonic anhydrase 2 inhibitor benzyl 2-[[2-[[(2S)-3-phenyl-2-... 2 9
Beta-secretase 1 inhibitor 1-N-[(2S,3R)-1-(3,5-difluorophenyl)... 8 7
Cathepsin E and Cathepsin D inhibitor SureCN2529506 family 2 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor AGN-PC-... 2 1
Beta-secretase 1 inhibitor SureCN12854847 family 1 0
Mineralocorticoid receptor ligand N-[3-[2-[cyclopropyl(methyl)... 1 0
Integrin alpha-V inhibitor (2R)-3-[(2-methoxybenzoyl)amino]-2-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00353361 CHEMBL344856 Bioactive AC1LA9LD
CFAMM00353353 CHEMBL139538 Bioactive AC1LA9K7
CFAMM00353346 CHEMBL342367 Bioactive AC1LA9L7
CFAMM00353339 CHEMBL139444 Bioactive AC1LA9L1
CFAMM00353338 CHEMBL263540 Bioactive AC1LA9KY
CFAMM00353363 CHEMBL342037 Bioactive AC1LA9LA
CFAMM00353349 CHEMBL343108 Bioactive AC1LA9KG

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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