CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM41882
Family Name Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3 alpha inhibitor 4-arylmaleimide deriv. 6t family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00518243 Functional Category Bioactive
Superfamily Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3 alpha Binder Superfamily 7
Class Class 516

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Tranilast Family 5 125
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Beta-ketoacyl-acyl carrier protein synthase III Inhibitor 2-(4... 2 6
Nuclear receptor ROR-gamma and Menin ligand CHEMBL1432265 family 1 18
Transient receptor potential cation channel subfamily V member... 1 2
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7496449 f... 3 2
Leukotriene A-4 hydrolase inhibitor SureCN5313952 family 4 1
Capsid scaffolding protein inhibitor AC1MHP20 family 3 3
Amine oxidase [flavin-containing] B and Adenosine receptor A2b... 2 2
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 0
3,5-bis[[2-(4-methoxyphenoxy)acetyl]amino]benzoate NP Agn-pc-0... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00518241 CHEMBL346493 Bioactive 4-arylmaleimide deriv. 6-s
CFAMM00518245 CHEMBL160829 Bioactive 4-arylmaleimide deriv. 6w
CFAMM00518243 CHEMBL160373 Bioactive 4-arylmaleimide deriv. 6t
CFAMM00518242 CHEMBL160231 Bioactive 4-arylmaleimide deriv. 6q

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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