CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4191
Family Name Cellular tumor antigen p53 inhibitor CHEMBL1395699 family
No. of Seeds 1 No. of Other Members 30
Family Centroid CFAMM00353637 Functional Category Bioactive with Natural Product
Superfamily Endothelin-1 receptor and Endothelin B receptor Binder Superfamily 7
Class Class 2976

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
Leukotriene B4 receptor 1 Ligand SB-201993 Family 5 13
Integrin beta-3 Inhibitor L-756568 Family 8 59
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
Platelet-derived growth factor receptor alpha and Platelet-der... 4 54
DNA topoisomerase 2-beta Inhibitor 3-(6-(furan-2-yl)-4-phenylp... 1 3
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
5-hydroxytryptamine receptor 3A Ligand 3alpha-(1'-methyl-2'-in... 2 17
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 7 44
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
Insulin-like growth factor-binding protein 4 and Insulin-like ... 4 44
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(1,3-... 21 11
Leukotriene B4 receptor 1 ligand SureCN8987047 family 4 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(1,3-... 2 9
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
D(3) dopamine receptor ligand N-[4-[4-(2,3-dichlorophenyl)pipe... 3 15
Cannabinoid receptor 1 ligand 5-cyano-N-(3-hydroxy-2,2-dimethy... 17 4
Coagulation factor X and Trypsin-1 inhibitor AGN-PC-0759OR family 4 7
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 5 12
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [5-(o... 4 4
Prostaglandin D2 receptor and Prostaglandin E2 receptor EP2 su... 2 0
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 2 11
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 4
Cytosolic phospholipase A2 inhibitor AGN-PC-00BH8R family 6 13
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4
3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor 4-(benzyloxy... 1 10
Beta-2 adrenergic receptor ligand SureCN4598646 family 7 7
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Endothelin-1 receptor and Endothelin B receptor ligand SureCN7... 3 7
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 7 1
Insulin-like growth factor-binding protein 3 inhibitor (1E)-1-... 2 0
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Mu-type opioid receptor ligand MITRAGYNINE family 2 8
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Coagulation factor X and Prothrombin inhibitor SureCN6434488 f... 3 13
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 0
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 2 3
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 6 5
Glutamate receptor 2 and Glutamate receptor 4 ligand SureCN828... 1 0
Aurora kinase A inhibitor SureCN3802792 family 2 3
Neurotensin receptor type 1 and Neurotensin receptor type 2 li... 1 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 1 0
Endothelin-1 receptor and Endothelin B receptor ligand AGN-PC-... 2 0
Indoles Metabolite Koeniginequinone B Family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27513 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543