CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM420
Family Name Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-1-cyano-2-(5-phenylthiophen-2-yl)ethyl]-3-thiophen-2-ylpropanamide family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00311397 Functional Category Bioactive
Superfamily 72 kDa type IV collagenase Inhibitor Batimastat Superfamily
Class Class 1376

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Temocapril Family 4 15
72 kDa type IV collagenase Inhibitor Batimastat Family 6 52
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(... 2 2
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-5-[4-(oxan-4-... 21 7
Substance-K receptor ligand N-[1-[[(2S)-5-[4-(dimethylsulfamoy... 9 16
Growth hormone secretagogue receptor type 1 ligand SureCN76469... 4 4
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Growth hormone secretagogue receptor type 1 ligand (2S)-2,6-di... 2 1
Pol polyprotein inhibitor AC1LA4ZN family 1 1
5-hydroxytryptamine receptor 1A ligand (3R)-N-(1-adamantyl)-1,... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00311393 CHEMBL1080602 Bioactive (2S)-2-amino-N-[(1S)-1-cyano-2-cyclohexylethyl]-3-thiophen-2-ylpropanamide
CFAMM00311397 CHEMBL1079888 Bioactive (2S)-2-amino-N-[(1S)-1-cyano-2-(5-phenylthiophen-2-yl)ethyl]-3-thiophen-2-ylpropanamide
CFAMM00311394 CHEMBL1081694 Bioactive (2S)-2-amino-N-[(1S)-1-cyano-2-naphthalen-2-ylethyl]-3-thiophen-2-ylpropanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45057 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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