CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4207
Family Name Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor ionotropic, NMDA 2A ligand CHEMBL335351 family
No. of Seeds 3 No. of Other Members 18
Family Centroid CFAMM00353776 Functional Category Bioactive
Superfamily Estradiol 17-beta-dehydrogenase 1 and DNA topoisomerase 1 Binder Superfamily
Class Class 1991

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Citric Acid family 2 58
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 13 26
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
Oestrogen receptor and Estrogen receptor beta Ligand Estrogen ... 7 2
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 38 35
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... 4 0
Glucocorticoid receptor ligand SureCN3894124 family 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 7 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00353776 CHEMBL335351 Bioactive CHEMBL335351
CFAMM00353780 CHEMBL139641 Bioactive CHEMBL139641
CFAMM00353773 CHEMBL52124 Bioactive CHEMBL52124

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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