CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4219
Family Name Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 inhibitor SureCN6990158 family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00354018 Functional Category Bioactive
Superfamily D(1B) dopamine receptor Ligand LE-300 Superfamily
Class Class 1105

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
Acetylcholinesterase Inhibitor Tacrine Family 12 515
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
Cholinesterase Inhibitor 9-[9-(beta-carboline-9-yl)nonyl]-beta... 7 7
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Kinesin-like protein KIF11 Inhibitor 2-(trifluoromethyl)-9h-ca... 5 0
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 10 18
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... 3 2
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 7,12-d... 1 0
Prostaglandin G/H synthase 2 Inhibitor 2-(4-(methylsulfonyl)ph... 7 33
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 1 11
Prostaglandin G/H synthase 2 inhibitor SureCN6998947 family 1 1
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 2 4
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 5 6
Melanin-concentrating hormone receptor 2 ligand N-[(1R)-1'-(9H... 4 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 0
Capsid scaffolding protein inhibitor AC1O583J family 5 1
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 1
CGMP-dependent protein kinase inhibitor AGN-PC-075INU family 1 1
Prostaglandin G/H synthase 2 inhibitor SureCN6345015 family 6 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00354019 CHEMBL139721 Bioactive AGN-PC-00PJIG
CFAMM00354018 CHEMBL143776 Bioactive SureCN6990158
CFAMM00354016 CHEMBL140167 Bioactive SureCN5331845
CFAMM00354020 CHEMBL341878 Bioactive SureCN6991877

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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