CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4220
Family Name Thyroid hormone receptor beta ligand CHEMBL1397256 family
No. of Seeds 1 No. of Other Members 12
Family Centroid CFAMM00354038 Functional Category Bioactive
Superfamily Microtubule-associated protein tau and Beta-lactamase Binder Superfamily 3
Class Class 994

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Benoxapr... 1 76
Substance-P receptor Ligand R 673 Family 2 127
C-C chemokine receptor type 2 and C-C motif chemokine 2 Ligand... 3 52
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Oestrogen receptor and Estrogen receptor beta Ligand 2-naphtha... 4 51
Oestrogen receptor and Estrogen receptor beta Ligand 2-(6-hydr... 9 22
Prostacyclin receptor and Prostaglandin E2 receptor EP3 subtyp... 4 17
Neuromedin-K receptor Ligand 3-methoxy-n',2-diphenylquinoline-... 14 33
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Peroxisome proliferator-activated receptor alpha Ligand BMS-68... 10 16
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 1 4
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 4 4
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[3-(1,3-be... 3 2
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Cysteinyl leukotriene receptor 1 ligand SureCN7808360 family 4 11
B2 bradykinin receptor ligand SureCN7012818 family 1 2
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
B2 bradykinin receptor ligand 4-[(E)-3-[[2-[2,4-dichloro-3-[[4... 29 2
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
B2 bradykinin receptor ligand SureCN6640854 family 7 4
Aldose reductase inhibitor SureCN1590315 family 1 7
Thromboxane-A synthase and Thromboxane A2 receptor ligand Sure... 5 37
Inosine-5'-monophosphate dehydrogenase inhibitor SureCN1318237... 2 12
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 4 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and Dual 3',5'... 27 20
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and Dual 3',5'... 11 0
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[4-phenyl-3-(tr... 2 3
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 1
Cholesteryl ester transfer protein inhibitor 2-(4-chloro-2,3-d... 1 1
Cysteinyl leukotriene receptor 1 ligand 4-oxo-7-[[3-(quinolin-... 4 17
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(2,6-di... 2 4
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 0
B2 bradykinin receptor ligand 1-N,3-N-dimethyl-4-[methyl-[2-[[... 4 1
D(4) dopamine receptor ligand SureCN8704964 family 1 2
Prothrombin inhibitor AGN-PC-074I2Z family 2 1
Cellular tumor antigen p53 inhibitor CHEMBL1592002 family 1 0
Cholesteryl ester transfer protein inhibitor AGN-PC-09QKST family 1 3
Cholesteryl ester transfer protein inhibitor N-[4-(5-chloro-7-... 1 0
Cholesteryl ester transfer protein inhibitor AGN-PC-07R9U4 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00354032 CHEMBL2336519 Bioactive N-[5-(5,7-dimethyl-1,3-benzoxazol-2-yl)-2-methylphenyl]-3-nitrobenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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