CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM42205
Family Name Tubulin beta-2B chain and Similar to alpha-tubulin isoform 1 inhibitor 2-(3-chlorophenyl)-6-pyrrolidin-1-yl-2,3-dihydro-1H-quinolin-4-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00518717 Functional Category Bioactive
Superfamily Ferritin light chain and Tubulin beta-2B chain Binder Superfamily
Class Class 2648

Cousin Family NamesSeedsMembers
Cruzipain Inhibitor 5-chloro-1-(4-chloro-benzyl)-1h-indole-2,3... 3 13
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Phospholipase D1 Inhibitor Halopemide Family 17 111
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
D(2) dopamine receptor Ligand PD-168077 Family 6 5
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor SureCN681575... 2 9
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Cellular tumor antigen p53 and Inositol monophosphatase 1 inhi... 1 12
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 2
D(4) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 4
Poly [ADP-ribose] polymerase 2 and Poly [ADP-ribose] polymeras... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00518717 CHEMBL16221 Bioactive 2-(3-chlorophenyl)-6-pyrrolidin-1-yl-2,3-dihydro-1H-quinolin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26816 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543