CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM42216
Family Name Steryl-sulfatase inhibitor [(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] formate family
No. of Seeds 1 No. of Other Members 9
Family Centroid CFAMM00518739 Functional Category Bioactive with Natural Product
Superfamily Steryl-sulfatase and Cytochrome P450 2C9 Binder Superfamily
Class Class 2073

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Oestrogen receptor Ligand Mestranol Family 2 29
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 12
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Peroxisome proliferator-activated receptor delta ligand SureCN... 1 0
Androgen receptor and Estrogen receptor ligand estradiol benzo... 1 29
Estradiol 17-beta-dehydrogenase 1 inhibitor SureCN4589665 family 2 4
Aromatase inhibitor AGN-PC-075LLF family 1 0
Putative NP ZINC03881930 Family 8 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00518739 CHEMBL1627728 Bioactive [(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] formate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27396 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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