CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM42349
Family Name Metabotropic glutamate receptor 2 ligand 8-chloro-6-[4-[(6-chloropyridin-3-yl)methoxy]phenyl]-2-propylisoquinolin-1-one family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00519129 Functional Category Bioactive
Superfamily Vasopressin V2 receptor and Vasopressin V1a receptor Binder Superfamily 2
Class Class 3170

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf inhibitor diaryl urea an... 12 93
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Cathepsin S and Cathepsin K inhibitor AGN-PC-09M7MI family 2 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 7
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 4 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00519124 CHEMBL1669386 Bioactive 8-chloro-2-propyl-6-(2-pyridin-3-ylethoxy)isoquinolin-1-one
CFAMM00519123 CHEMBL1669387 Bioactive 8-chloro-2-propyl-6-(3-pyridin-3-ylpropoxy)isoquinolin-1-one
CFAMM00519129 CHEMBL1669399 Bioactive 8-chloro-6-[4-[(6-chloropyridin-3-yl)methoxy]phenyl]-2-propylisoquinolin-1-one
CFAMM00519122 CHEMBL1669391 Bioactive 8-chloro-6-(5-fluoro-6-methoxypyridin-3-yl)-2-propylisoquinolin-1-one
CFAMM00519128 CHEMBL1669397 Bioactive 8-chloro-2-propyl-6-(4-pyridin-4-yloxyphenyl)isoquinolin-1-one
CFAMM00519121 CHEMBL1669400 Bioactive 8-chloro-2-propyl-6-[4-[[6-(trifluoromethyl)pyridin-3-yl]methoxy]phenyl]isoquinolin-1-one
CFAMM00519127 CHEMBL1669394 Bioactive 8-chloro-2-propyl-6-[6-(pyridin-3-ylmethoxy)pyridin-3-yl]isoquinolin-1-one
CFAMM00519126 CHEMBL1669393 Bioactive 8-chloro-6-[6-(2-phenylethoxy)pyridin-3-yl]-2-propylisoquinolin-1-one
CFAMM00519125 CHEMBL1669392 Bioactive 8-chloro-6-(6-phenoxypyridin-3-yl)-2-propylisoquinolin-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

81384 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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