CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4235
Family Name Substance-P receptor ligand 1-[4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidin-1-yl]ethanone family
No. of Seeds 5 No. of Other Members 8
Family Centroid CFAMM00354304 Functional Category Bioactive
Superfamily Substance-P receptor and C-C chemokine receptor type 2 Binder Superfamily
Class Class 100

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Substance-P receptor Ligand L-733060 Family 19 71
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Substance-P receptor Ligand SCH-388714 Family 26 8
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 5 14
Substance-P receptor ligand (1S,2R)-2-[(1R)-1-[3,5-bis(trifluo... 12 0
Substance-P receptor ligand (2S)-3-[[3,5-bis(trifluoromethyl)p... 1 4
Substance-P receptor ligand SureCN8112982 family 1 0
Substance-P receptor ligand 4-[[3,5-bis(trifluoromethyl)phenyl... 2 1
Substance-P receptor and Potassium voltage-gated channel subfa... 10 0
Substance-P receptor ligand 1-[[(1R,2R,3S)-3-[[3,5-bis(trifluo... 4 3
Substance-P receptor ligand 1-amino-3-[[(1R)-1-[3,5-bis(triflu... 5 0
Substance-P receptor ligand 1-[(1R,2S,3S)-3-[[3,5-bis(trifluor... 7 2
Substance-P receptor ligand AGN-PC-03NGZP family 3 0
Substance-P receptor ligand 2-[[(1R,2S,3S)-3-[(1R)-1-[3,5-bis(... 5 0
Substance-P receptor ligand 1-[3-[[(1R)-1-[3,5-bis(trifluorome... 2 0
Substance-P receptor and Neuromedin-K receptor ligand 3-[[(1R)... 1 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 1
Sodium-dependent serotonin transporter and Substance-P recepto... 2 2
Substance-P receptor and Sodium-dependent serotonin transporte... 6 1
Substance-P receptor ligand 1-[(3S,4R)-3-[(1R)-1-[3,5-bis(trif... 9 0
Substance-P receptor ligand methyl 2-[(2S,3S)-2-[[3,5-bis(trif... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00354299 CHEMBL357887 Bioactive AGN-PC-00GF2O
CFAMM00354304 CHEMBL139784 Bioactive 1-[4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidin-1-yl]ethanone
CFAMM00354296 CHEMBL143375 Bioactive 1-[4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidin-1-yl]-2-(dimethylamino)ethanone
CFAMM00354301 CHEMBL341599 Bioactive 1-[4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidin-1-yl]-4-(dimethylamino)butan-1-one
CFAMM00354300 CHEMBL143156 Bioactive 1-[4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidin-1-yl]-2-pyrrolidin-1-ylethanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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