CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4240
Family Name Apolipoprotein B-100 and Microsomal triglyceride transfer protein large subunit inhibitor 3,5-dimethyl-N-[(2R)-2-(thiophen-2-ylsulfonylamino)-2,3-dihydro-1H-inden-5-yl]-2-[4-(trifluoromethyl)phenyl]benzamide family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00354328 Functional Category Bioactive
Superfamily Apolipoprotein B-100 and Histone deacetylase 1 Binder Superfamily
Class Class 4011

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
C-C chemokine receptor type 8 Ligand N-(4-phenylsulfamoyl-naph... 4 62
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(4,5-dichlo... 4 9
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-[1-(naphtha... 13 5
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-[1-[(2,4-di... 8 2
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 10 0
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 3 0
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 3 0
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 6 5
Thyroid hormone receptor beta and Cellular tumor antigen p53 l... 1 4
Prelamin-A/C inhibitor CHEMBL1547148 family 1 8
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 6 9
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 0
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Histone deacetylase 1 inhibitor SureCN3642893 family 10 23
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 10 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
Vascular endothelial growth factor receptor 2 ligand isoindoli... 1 0
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00354329 CHEMBL336873 Bioactive 3-methyl-N-[(2R)-2-(thiophen-2-ylsulfonylamino)-2,3-dihydro-1H-inden-5-yl]-2-[4-(trifluoromethyl)phenyl]benzamide
CFAMM00354328 CHEMBL139834 Bioactive 3,5-dimethyl-N-[(2R)-2-(thiophen-2-ylsulfonylamino)-2,3-dihydro-1H-inden-5-yl]-2-[4-(trifluoromethyl)phenyl]benzamide
CFAMM00354327 CHEMBL142272 Bioactive SureCN13591659
CFAMM00354326 CHEMBL356091 Bioactive SureCN13591639
CFAMM00354325 CHEMBL344849 Bioactive 3,5-dimethyl-N-[(2S)-2-(thiophen-2-ylsulfonylamino)-2,3-dihydro-1H-inden-5-yl]-2-[4-(trifluoromethyl)phenyl]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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