CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM42432
Family Name Muscarinic acetylcholine receptor M2 ligand 2-[3-[(E)-[1-[6-[4-[(E)-3-(1,3-dioxoisoindol-2-yl)propoxyiminomethyl]pyridin-1-ium-1-yl]hexyl]pyridin-1-ium-4-yl]methylideneamino]oxypropyl]isoindole-1,3-dione;dibromide family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00519272 Functional Category Bioactive
Superfamily Reverse transcriptase/RNaseH and Peptide deformylase Binder Superfamily
Class Class 295

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
Substance-P receptor Ligand TAK-637 Family 18 63
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Transient receptor potential cation channel subfamily V member... 6 23
D(4) dopamine receptor Ligand ABT-670 Family 4 14
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Histamine H3 receptor ligand AGN-PC-04YWRD family 5 13
Histamine H3 receptor ligand SureCN1857507 family 1 4
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 20 2


CFAM Mol ID

External ID

Functional Category

Molecule Name
CFAMM00519272 CHEMBL169633 Bioactive 2-[3-[(E)-[1-[6-[4-[(E)-3-(1,3-dioxoisoindol-2-yl)propoxyiminomethyl]pyridin-1-ium-1-yl]hexyl]pyridin-1-ium-4-yl]methylideneamino]oxypropyl]isoindole-1,3-dione;dibromide
CFAMM00519276 CHEMBL354103 Bioactive 2-[3-[(E)-[1-[5-[4-[(E)-3-(1,3-dioxoisoindol-2-yl)propoxyiminomethyl]pyridin-1-ium-1-yl]pentyl]pyridin-1-ium-4-yl]methylideneamino]oxypropyl]isoindole-1,3-dione;dibromide
CFAMM00519275 CHEMBL169342 Bioactive 2-[[(E)-[1-[3-[4-[(E)-(1,3-dioxoisoindol-2-yl)methoxyiminomethyl]pyridin-1-ium-1-yl]propyl]pyridin-1-ium-4-yl]methylideneamino]oxymethyl]isoindole-1,3-dione;dibromide
CFAMM00519274 CHEMBL169475 Bioactive 2-[3-[(E)-[1-[3-[4-[(E)-3-(1,3-dioxoisoindol-2-yl)propoxyiminomethyl]pyridin-1-ium-1-yl]propyl]pyridin-1-ium-4-yl]methylideneamino]oxypropyl]isoindole-1,3-dione;dibromide
CFAMM00519273 CHEMBL169638 Bioactive 2-[3-[(E)-[1-[4-[4-[(E)-3-(1,3-dioxoisoindol-2-yl)propoxyiminomethyl]pyridin-1-ium-1-yl]butyl]pyridin-1-ium-4-yl]methylideneamino]oxypropyl]isoindole-1,3-dione;dibromide

Statistics of CFAM Database
 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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