CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4251
Family Name Interstitial collagenase and Collagenase 3 inhibitor (3S)-4-(4-bromophenyl)sulfonyl-N-hydroxy-2,2-dimethyl-1,4-thiazepane-3-carboxamide family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00354409 Functional Category Bioactive
Superfamily Collagenase 3 and Interstitial collagenase Binder Superfamily 3
Class Class 3512

Cousin Family NamesSeedsMembers
Disintegrin and metalloproteinase domain-containing protein 17... 7 39
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 6
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 1


External ID

Functional Category

Molecule Name

CFAMM00354407 CHEMBL139886 Bioactive (3S)-4-(4-bromo-2-methylphenyl)sulfonyl-N-hydroxy-2,2-dimethyl-1,4-thiazepane-3-carboxamide
CFAMM00354410 CHEMBL334909 Bioactive (3S)-4-(4-bromophenyl)sulfonyl-N-hydroxy-2,2-dimethyl-1,1-dioxo-1,4-thiazepane-3-carboxamide
CFAMM00354409 CHEMBL140511 Bioactive (3S)-4-(4-bromophenyl)sulfonyl-N-hydroxy-2,2-dimethyl-1,4-thiazepane-3-carboxamide
CFAMM00354408 CHEMBL316978 Bioactive 4-benzylsulfanyl-2-[(4-bromophenyl)sulfonyl-(2-methylpropyl)amino]-N-hydroxybutanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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