CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM42596
Family Name Calpain-1 catalytic subunit inhibitor (2E)-2-[(3,4-dihydroxyphenyl)methylidene]-N-[(2S)-4-[2-(4-methoxyphenyl)ethylamino]-3,4-dioxo-1-phenylbutan-2-yl]butanamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00519713 Functional Category Bioactive
Superfamily Beta-lactamase and Cholinesterase Binder Superfamily 6
Class Class 3513

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Zucapsacin family 7 177
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 6 40
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Transient receptor potential cation channel subfamily V member... 2 6
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Transient receptor potential cation channel subfamily V member... 3 18
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Pol polyprotein inhibitor AC1LA3AI family 5 9
Beta-lactamase inhibitor CHEMBL1316873 family 1 1
Adenosine receptor A2a and Adenosine receptor A2b ligand N-(2-... 3 0
72 kDa type IV collagenase and Aminopeptidase N inhibitor meth... 1 1
Carbonic anhydrase and Carbonic anhydrase 2 inhibitor 2-(3-chl... 2 0
Amino Acids and Derivatives Metabolite Caffeoyl aspartic acid ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00519713 CHEMBL1770880 Bioactive (2E)-2-[(3,4-dihydroxyphenyl)methylidene]-N-[(2S)-4-[2-(4-methoxyphenyl)ethylamino]-3,4-dioxo-1-phenylbutan-2-yl]butanamide
CFAMM00519718 CHEMBL1771026 Bioactive (2E)-2-[(4-hydroxy-3-methoxyphenyl)methylidene]-N-[(2S)-4-[2-(4-methoxyphenyl)ethylamino]-3,4-dioxo-1-phenylbutan-2-yl]hexanamide
CFAMM00519717 CHEMBL1771024 Bioactive (2E)-2-[(3,4-dihydroxyphenyl)methylidene]-N-[(2S)-4-[2-(4-methoxyphenyl)ethylamino]-3,4-dioxo-1-phenylbutan-2-yl]hexanamide
CFAMM00519715 CHEMBL1770882 Bioactive (2E)-2-[(3,4-dihydroxyphenyl)methylidene]-N-[(2S)-4-[2-(4-methoxyphenyl)ethylamino]-3,4-dioxo-1-phenylbutan-2-yl]pentanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27074 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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