CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4281
Family Name 5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine receptor 3D ligand N,N-dimethyl-2-[(Z)-(3-methylthieno[2,3-b]pyrrolizin-8-ylidene)amino]oxyethanamine family
No. of Seeds 8 No. of Other Members 5
Family Centroid CFAMM00354638 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine receptor 3B Binder Superfamily
Class Class 4020

Cousin Family NamesSeedsMembers
Cytochrome P450 3A4 Inhibitor 3-(3-methylthiophen-2-yl)pyridin... 5 27
Metabotropic glutamate receptor 5 Ligand 2-methyl-4-(pyridin-3... 10 35
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
Arachidonate 5-lipoxygenase inhibitor AGN-PC-073JGI family 1 0


External ID

Functional Category

Molecule Name

CFAMM00354638 CHEMBL334923 Bioactive N,N-dimethyl-2-[(Z)-(3-methylthieno[2,3-b]pyrrolizin-8-ylidene)amino]oxyethanamine
CFAMM00354647 CHEMBL141413 Bioactive AGN-PC-075OIG
CFAMM00354643 CHEMBL143489 Bioactive AGN-PC-075ONK
CFAMM00354646 CHEMBL336922 Bioactive AGN-PC-075OMZ
CFAMM00354642 CHEMBL342138 Bioactive AGN-PC-075ONX
CFAMM00354645 CHEMBL140105 Bioactive AGN-PC-075ONZ
CFAMM00354640 CHEMBL344248 Bioactive AGN-PC-075ONY
CFAMM00354639 CHEMBL141044 Bioactive AGN-PC-075OIN

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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