CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM42820
Family Name Vesicular acetylcholine transporter and Sigma non-opioid intracellular receptor 1 ligand (4-fluorophenyl)-[1-[(3S,4S)-4-hydroxy-1-(pyridin-3-ylmethyl)piperidin-3-yl]piperidin-4-yl]methanone family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00520197 Functional Category Bioactive
Superfamily CP-18770 Superfamily
Class Class 295

Cousin Family NamesSeedsMembers
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
SUR2-type K(ATP) channel Ligand Nicorandil Family 5 85
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Substance-P receptor Ligand TAK-637 Family 18 63
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
Integrin beta-3 Inhibitor Elarofiban Family 28 45
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Transient receptor potential cation channel subfamily V member... 6 23
D(4) dopamine receptor Ligand ABT-670 Family 4 14
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... 11 26
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Dipeptidyl peptidase 4 inhibitor (1S,3S,5S)-2-[(2S)-2-amino-2-... 3 5
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745NK family 2 6
Neuronal acetylcholine receptor subunit alpha-7 and Acetylchol... 2 3
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04SK7R family 3 3
Substance-K receptor ligand N-[1-[[(2R)-5-[4-(oxan-4-ylmethyl)... 2 0
Metabotropic glutamate receptor 5 ligand AGN-PC-0A9SVV family 2 12
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 20 2
Probable G-protein coupled receptor 142 ligand (2S)-N-(2-oxo-5... 2 1
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... 6 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00520198 CHEMBL2047123 Bioactive (4-fluorophenyl)-[1-[(3R,4R)-4-hydroxy-1-(pyridine-3-carbonyl)piperidin-3-yl]piperidin-4-yl]methanone;oxalic acid
CFAMM00520197 CHEMBL1822404 Bioactive (4-fluorophenyl)-[1-[(3S,4S)-4-hydroxy-1-(pyridin-3-ylmethyl)piperidin-3-yl]piperidin-4-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24517 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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