CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM4289
Family Name Melanocortin receptor 4 and Melanocortin receptor 3 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)-1-[4-cyclohexyl-4-[(1-methyltetrazol-5-yl)methyl]piperidin-1-yl]-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide family
No. of Seeds 8 No. of Other Members 3
Family Centroid CFAMM00354701 Functional Category Bioactive
Superfamily Melanocortin receptor 4 and Melanocortin receptor 3 Binder Superfamily
Class Class 3903

Cousin Family NamesSeedsMembers
Substance-P receptor ligand (2S)-N-[(2S)-1-[benzyl(methyl)amin... 5 9
Melanocortin receptor 4 ligand (2R)-N-[(2R)-3-(4-chlorophenyl)... 1 22
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (3S... 7 10
Melanocortin receptor 4 and Melanocortin receptor 5 ligand AC1... 7 31
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 7 16
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (3R... 7 1
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (3R... 6 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00354698 CHEMBL249277 Bioactive (3R)-N-[(2S)-3-(4-chlorophenyl)-1-[4-hexyl-4-[(1-methyltetrazol-5-yl)methyl]piperidin-1-yl]-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
CFAMM00354697 CHEMBL398816 Bioactive (3R)-N-[(2S)-3-(4-chlorophenyl)-1-[4-(2-methylpropyl)-4-[(1-methyltetrazol-5-yl)methyl]piperidin-1-yl]-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
CFAMM00354703 CHEMBL399714 Bioactive (3R)-N-[(2S)-3-(4-chlorophenyl)-1-[4-(4-chlorophenyl)-4-[(1-methyltetrazol-5-yl)methyl]piperidin-1-yl]-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
CFAMM00354702 CHEMBL400252 Bioactive (3R)-N-[(2S)-3-(4-chlorophenyl)-1-[4-(2,2-dimethylpropyl)-4-[(1-methyltetrazol-5-yl)methyl]piperidin-1-yl]-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
CFAMM00354695 CHEMBL400456 Bioactive (3R)-N-[(2S)-1-[4-butan-2-yl-4-[(1-methyltetrazol-5-yl)methyl]piperidin-1-yl]-3-(4-chlorophenyl)-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
CFAMM00354701 CHEMBL140154 Bioactive (3R)-N-[(2R)-3-(4-chlorophenyl)-1-[4-cyclohexyl-4-[(1-methyltetrazol-5-yl)methyl]piperidin-1-yl]-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
CFAMM00354700 CHEMBL140738 Bioactive (3R)-N-[(2R)-3-(4-chlorophenyl)-1-[4-cyclohexyl-4-[(2-methyltetrazol-5-yl)methyl]piperidin-1-yl]-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
CFAMM00354699 CHEMBL250508 Bioactive (3R)-N-[(2S)-3-(4-chlorophenyl)-1-[4-cyclohexyl-4-[(1-methyltetrazol-5-yl)methyl]piperidin-1-yl]-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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