CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM429
Family Name 3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor (9aR,11aS)-N-(2-chlorophenyl)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00007899 Functional Category Bioactive
Superfamily 3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-steroid 4-dehydrogenase 2 Binder Superfamily 2
Class Class 3154

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
Bifunctional epoxide hydrolase 2 Inhibitor N-(3-chloro-phenyl)... 2 43
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 4 8
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 15 24
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 7 0
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 4 1
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 4 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 0
P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-[2-(1-hydroxy-3... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00311462 CHEMBL86832 Bioactive (1S,9aR,11aS)-N-[2-chloro-6-(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
CFAMM00311459 CHEMBL109170 Bioactive (9aR,11aS)-N-(4-chlorophenyl)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21768 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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