CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM42915
Family Name Trypanothione reductase inhibitor 3-(6-chloro-2-methyl-4-phenyl-4H-quinazolin-3-yl)-N,N-dimethylpropan-1-amine family
No. of Seeds 9 No. of Other Members 1
Family Centroid CFAMM00520625 Functional Category Bioactive
Superfamily Acetylcholinesterase and Trypanothione reductase Binder Superfamily
Class Class 2027

Cousin Family NamesSeedsMembers
Benzodiazepine receptor ligand benzodiazepine derivative Fludi... 11 78
Gamma-aminobutyric acid receptor subunit alpha-1 ligand benzod... 1 2
5-hydroxytryptamine receptor 2A and Alpha-1A adrenergic recept... 1 19
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 7 27
Acetylcholinesterase inhibitor SureCN8968422 family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00520622 CHEMBL1836365 Bioactive 3-benzyl-6-chloro-2-methyl-4-phenyl-4H-quinazoline
CFAMM00520628 CHEMBL1836603 Bioactive 3-[6-chloro-2-methyl-4-(4-methylphenyl)-4H-quinazolin-3-yl]-N,N-dimethylpropan-1-amine
CFAMM00520627 CHEMBL1836378 Bioactive 6-chloro-2-methyl-3-[2-(4-methylpiperazin-1-yl)ethyl]-4-phenyl-4H-quinazoline
CFAMM00520626 CHEMBL1836606 Bioactive 6-chloro-4-(3-fluorophenyl)-2-methyl-3-(2-piperidin-1-ylethyl)-4H-quinazoline
CFAMM00520625 CHEMBL1836380 Bioactive 3-(6-chloro-2-methyl-4-phenyl-4H-quinazolin-3-yl)-N,N-dimethylpropan-1-amine
CFAMM00520631 CHEMBL1836615 Bioactive 6-chloro-2-methyl-4-(4-methylphenyl)-3-(2-piperidin-1-ylethyl)-4H-quinazoline
CFAMM00520630 CHEMBL1836371 Bioactive 3-[(6-chloro-2-methyl-4-phenyl-4H-quinazolin-3-yl)methyl]-N,N-dimethylaniline
CFAMM00520623 CHEMBL1836368 Bioactive 6-chloro-3-[(2-fluorophenyl)methyl]-2-methyl-4-phenyl-4H-quinazoline
CFAMM00520629 CHEMBL1836612 Bioactive 6-chloro-4-(4-chlorophenyl)-2-methyl-3-(2-piperidin-1-ylethyl)-4H-quinazoline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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