CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM42985
Family Name Estradiol 17-beta-dehydrogenase 2 inhibitor (4R,5R)-5-[(1S)-3-(2-fluorophenyl)-1-hydroxyprop-2-ynyl]-1-methyl-4-phenylpyrrolidin-2-one family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00520830 Functional Category Bioactive
Superfamily Estradiol 17-beta-dehydrogenase 2 Binder Superfamily 2
Class Class 5131

Cousin Family NamesSeedsMembers
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 4 41
Estradiol 17-beta-dehydrogenase 2 inhibitor (4R,5R)-5-[(S)-hyd... 2 1
Estradiol 17-beta-dehydrogenase 2 inhibitor (4R,5R)-5-[(S)-(3-... 3 0


External ID

Functional Category

Molecule Name

CFAMM00520833 CHEMBL189767 Bioactive (4R,5R)-5-[(1S)-3-(4-fluorophenyl)-1-hydroxyprop-2-ynyl]-1-methyl-4-phenylpyrrolidin-2-one
CFAMM00520832 CHEMBL188447 Bioactive (4R,5R)-5-[(1S)-1-hydroxy-3-phenylprop-2-ynyl]-1-methyl-4-phenylpyrrolidin-2-one
CFAMM00520831 CHEMBL361091 Bioactive (4R,5R)-5-[(1S)-1-hydroxy-3-(4-methylphenyl)prop-2-ynyl]-1-methyl-4-phenylpyrrolidin-2-one
CFAMM00520830 CHEMBL188755 Bioactive (4R,5R)-5-[(1S)-3-(2-fluorophenyl)-1-hydroxyprop-2-ynyl]-1-methyl-4-phenylpyrrolidin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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