CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM43124
Family Name Tyrosine-protein kinase inhibitor (4-chloro-1H-indol-2-yl)-[(3R)-1'-pyrrolidin-3-ylspiro[2H-indole-3,3'-pyrrolidine]-1-yl]methanone family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00521150 Functional Category Bioactive
Superfamily Adenosine receptor A3 and 14-alpha sterol demethylase Binder Superfamily
Class Class 952

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Reverse transcriptase Inhibitor IDX899 Family 2 118
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Cannabinoid receptor 1 ligand AGN-PC-04YSUM family 7 6
Translocator protein inhibitor (2E)-N-(4-chlorophenyl)-N-methy... 2 13
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 3 5
Poly [ADP-ribose] polymerase 1 inhibitor SureCN4998361 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00521150 CHEMBL1933549 Bioactive (4-chloro-1H-indol-2-yl)-[(3R)-1'-pyrrolidin-3-ylspiro[2H-indole-3,3'-pyrrolidine]-1-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27620 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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