CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM43132
Family Name Perforin-1 inhibitor (5E)-5-[[5-(1-oxo-3H-2-benzofuran-5-yl)-1H-indol-2-yl]methylidene]-2-sulfanylideneimidazolidin-4-one family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00521163 Functional Category Bioactive
Superfamily Perforin-1 Binder Superfamily 2
Class Class 5322

Cousin Family NamesSeedsMembers
Nuclear receptor ROR-gamma and Microtubule-associated protein ... 1 6


External ID

Functional Category

Molecule Name

CFAMM00521164 CHEMBL1934386 Bioactive (5E)-5-[[6-(1-oxo-3H-2-benzofuran-5-yl)quinolin-2-yl]methylidene]-2-sulfanylideneimidazolidin-4-one
CFAMM00521163 CHEMBL1934384 Bioactive (5E)-5-[[5-(1-oxo-3H-2-benzofuran-5-yl)-1H-indol-2-yl]methylidene]-2-sulfanylideneimidazolidin-4-one
CFAMM00521166 CHEMBL1934370 Bioactive (5E)-5-[[5-(1-oxo-3H-2-benzofuran-5-yl)pyridin-2-yl]methylidene]-2-sulfanylideneimidazolidin-4-one
CFAMM00521165 CHEMBL1934383 Bioactive (5E)-5-[[6-(1-oxo-3H-2-benzofuran-5-yl)-1H-indol-2-yl]methylidene]-2-sulfanylideneimidazolidin-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



107144 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543