CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM43169
Family Name Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor propan-2-yl (E)-3-(4-hydroxyphenyl)prop-2-enoate family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00521229 Functional Category Bioactive with Human Metabolite
Superfamily Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor propan-2-yl (E)-3-(4-hydroxyphenyl)prop-2-enoate Superfamily
Class Class 2550

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Prostaglandin G/H synthase 1 Inhibitor Salicyclic Acid Family 3 39
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Oestrogen receptor ligand Dienestrol Family 35 440
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Arachidonate 5-lipoxygenase Inhibitor Caffeic Acid Family 3 32
Bile acid receptor Ligand SR-45023A (apomine) Family 3 34
Macrophage migration inhibitory factor and Prothrombin Inhibit... 2 49
Proto-oncogene tyrosine-protein kinase Src Inhibitor Malonic A... 1 34
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Steryl-sulfatase Inhibitor 4-sulfamoyloxy-benzoic Acid Hexyl E... 11 1
4-aminobutyrate aminotransferase, mitochondrial and Succinate-... 4 22
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Squalene monooxygenase Inhibitor Octyl_gallate Family 5 5
Aromatase Inhibitor NSC-122427 Family 1 0
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 6-meth... 2 36
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-54162 Family 1 3
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor P-coum... 1 1
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-methoxybenzenemethan... 2 26
Tyrosinase Inhibitor 3-(2,4-dihydroxyphenyl)-propionic Acid Et... 3 8
Androgen receptor Ligand Palodesangren E Family 12 43
DNA polymerase Inhibitor 3alpha-o-trans-p-coumaroyl-7-labden-1... 1 13
Histone deacetylase 2 and Histone deacetylase 8 inhibitor 2-hy... 1 0
Protein kinase C delta type and Protein kinase C alpha type in... 1 10
Glycogen phosphorylase, muscle form and Glycogen phosphorylase... 1 2
G2/mitotic-specific cyclin-B1 and Cyclin-dependent kinase 1 in... 2 8
Eukaryotic elongation factor 2 kinase and Proto-oncogene tyros... 1 1
Benzoic Acid and Derivatives Metabolite Methyl 3-(2,3-dihydrox... 1 3
Benzyloxycarbonyls Metabolite 4-Methoxybenzyl formate Family 1 7
Phenols and Derivatives Metabolite 2-(Ethoxymethyl)phenol Family 1 14
Putative NP ZINC04012191 Family 2 2
[(E)-3-carboxy-2-(5-methyl-2-oxidophenyl)prop-2-enyl]-(2-pheny... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00521221 CHEMBL2391084 Bioactive (2R)-2-[(2R)-2-fluoro-4-(4-hydroxyphenyl)butyl]-2,3-dihydropyran-6-one
CFAMM00521229 CHEMBL1940391 Bioactive propan-2-yl (E)-3-(4-hydroxyphenyl)prop-2-enoate
CFAMM00521228 CHEMBL2074640 Bioactive ethyl (E)-3-(4-hydroxyphenyl)prop-2-enoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27639 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543